Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

ADL 5859

CAS 850173-95-4

C24H28N2O3.HCl  MW 428.95

Purity: 99 %

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1751  Prime Source

Qty1: 10 mg (research sample) / €115  $150

Qty2: 50 mg (research sample) / €415  $540

Qty3: on request

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Biological Activity:   Highly potent and selective δ opioid receptor agonist with Ki value to be 0.84 nM and ED50 value to be 20 nM.   References: B Le Bourdonnec et al. Potent, orally bioavailable delta opioid receptor agonists for the treatment of pain: discovery of N,N-diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide (ADL5859). J. Med. Chem. 2008, 51(19), 5893-5896. [online]     Chemical Name: N,N-Diethyl-4-(5-hydroxyspiro[chromene-2,4'-piperidine]-4-yl)benzamide

ADL 5859 | Delta opioid agonist | Axon Medchem | Axon 1751 | ADL5859

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Axon Opioid Receptor Ligands:

nor-BNI | k opioid antagonist

β-FNA | μ opioid antagonist

GNTI | k opioid antagonist

Nalmefene | opioid antagonist

Naloxonazine | opioid antagonist

Naloxone Benzoylhydrazone

BAN ORL 24 | NOP antagonist

JTC 801 | NOP antagonist

SB 612111 | NOP antagonist