AZ 12216052 | mGluR8 PAM | Axon Medchem | Axon 1747

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AZ 12216052

CAS 1290628-31-7

C19H22BrNOS MW 392.35

Purity: 98%

Soluble in DMSO to >100 mM

Ordering Information:

Cat. No. Axon 1747 Prime Source

Qty1: 10 mg / 125 $163

Qty2: 50 mg / 425 $553

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

A positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 8 (mGluR8)

References:

RM Duvoisin et al. Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges. Behav. Brain Res. 2011, 221(1), 50-54. [online]

RM Duvoisin et al, Acute pharmacological modulation of mGluR8 reduces measures of anxiety. Behav. Brain Res. 2010, 212(2), 168-173. [online]

Chemical Name: 2-(4-bromobenzylthio)-N-(4-sec-butylphenyl)acetamide

AZ 12216052 | mGluR8 PAM | Axon Medchem | Axon 1747 | AZ12216052

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.