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PAC-1

Procaspase Activating Compound 1

CAS 315183-21-2

C23H28N4O2 MW 392.49

Purity: 99%

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1743   Prime Source Promotion

Qty1: 10 mg / €80  $104

Qty2: 50 mg / €200  $260

Qty3: on request

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or by fax to: +31-50-3600390.

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Biological Activity:   A procaspase activating compound activates procaspase-3 to produce caspase-3; induces apoptosis in cancerous cells.   References: online   KS Putt et al. Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat. Chem. Biol. 2006, 2(10), 543–50. [online]   QP Peterson et al. PAC-1 Activates Procaspase-3 in vitro Through Relief of Zinc-Mediated Inhibition. J. Mol. Biol. 2009, 388, 144-158. [online]     Chemical Name: N'-(3-allyl-2-hydroxybenzylidene)-2-(4-benzylpiperazin-1-yl)acetohydrazide

PAC-1 | Procaspase activator | Axon Medchem | Axon 1743 | PAC1

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