CaSR antagonist | Axon Medchem

	Chemistry Service Platform - CRO in Medicinal Chemistry × close
Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

CaSR antagonist 18c

CAS 802916-30-8

C32H35N3O6 MW 557.64

Purity: 99% (optically pure)

Soluble in DMSO to 79 mM

Ordering Information:

Cat. No. Axon 1732 Exclusive promtion

Qty1: 5 mg (research sample) / 135 $176

Qty2: 25 mg (research sample) / 475 $618

Qty3: on request contract research sample

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Calcium-sensing receptor (CaSR) antagonist (IC50: 76 nM); potential anabolic agent for the treatment of osteoporsis.

References:

W Yang et al. Discovery and Structure−Activity Relationships of Trisubstituted Pyrimidines/Pyridines as Novel Calcium-Sensing Receptor Antagonists. J. Med. Chem. 2009, 52(4), 12041208. [online]

Chemical Name: (S)-6-(1-hydroxy-3-phenylpropan-2-ylamino)-N-(2-phenoxyethyl)-2-(3,4,5-trimethoxyphenyl)nicotinamide

CaSR antagonist | Axon Medchem | Axon 1732

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com Š 2012

Axon Ligands In The Field:

CaSR antagonist | Axon 1732