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PF 3845

 

 

CAS 1196109-52-0

C24H23F3N4O2  MW 456.46

Purity: 99%

Soluble in 1 eq aq HCl to 40 mM

Soluble in DMSO to 100 mM

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1711  Prime Source Promotion

 

Qty1: 10 mg / €115  $150

 

Qty2: 50 mg / €435  $566

 

Qty3: on request

 

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Biological Activity:

 

Highly selective and irreversible fatty acid amide hydrolase (FAAH) inhibitor

 

References:

 

K Ahn et al. Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chem. Biol. 2009, 16, 411-420. [online]

 

L Booker  et al. The FAAH Inhibitor PF-3845 Acts in the Nervous System to Reverse Lipopolysaccharide-induced Tactile Allodynia in Mice. Br. J. Pharmacol. 2011 Apr 20. doi: 10.1111/j.1476-5381.2011.01445.x. [online]

 

 

 

Chemical Name: N-3-Pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidine carboxamide

 

PF 3845 | FAAH inhibitor | Axon Medchem | Axon 1711 | PF3845

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

PF 3845 | FAAH inhibitor

 

 

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