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WAY 208466 dihydrochloride

CAS 1207064-61-6

633304-27-5 (free base)

C17H18FN3O2S.2HCl  MW 420.33

Purity: 99 %

Soluble in water and DMSO

Ordering Information:

Cat. No. Axon 1710     Prime Source

Qty1: 10 mg (research sample) / €125  $163

Qty2: 50 mg (research sample) / €450  $585

Qty3: on request

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Biological Activity:   Potent and highly selective serotonin 5-HT6 receptor agonist (EC50: 7.3 nM); increases GABA levels in the cerebral cortex; produces antidepressant and anxiolytic effects in rodents; useful in the treatment of obsessive-compulsive disorder (OCD).   References:   LE Schechter et al. Neuropharmacological Profile of Novel and Selective 5-HT6 Receptor Agonists: WAY-181187 and WAY-208466. Neuropsychopharmacology 2008, 33, 1323–1335. [online]   GV Carr et al. Antidepressant and anxiolytic effects of selective 5-HT(6) receptor agonists in rats. Psychopharmacology 2010, 213(2–3), 499–507. [online]     Chemical Name: 2-(3-(3-fluorophenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)-N,N-dimethylethanamine dihydrochloride

WAY 208466 | 5-HT6 agonist | Axon Medchem | Axon 1710 | WAY208466

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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