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Bexarotene

SR 11247 - Targretin

 

 

CAS 153559-49-0 

C24H28O2  MW 348.48

Purity: 99%

Soluble in DMSO

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1700     

 

Qty1: 10 mg (research sample) / €85  $111

 

Qty2: 50 mg (research sample) / €235  $306

 

Qty3: on request

 

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or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Selective agonist for retinoid X receptors (RXR); An oral antineoplastic agent indicated for cutaneous T cell lymphoma (CTCL).

 

References: online

 

R Gniadecki et al. The optimal use of bexarotene in cutaneous T-cell lymphoma. Br. J. Dermatol. 2007, 157(3), 433–440. [online]

 

KH Dragnev et al. A proof-of-principle clinical trial of bexarotene in patients with non-small cell lung cancer. Clin Cancer Res. 2007, 13(6), 1794-800. [online]

 

 

 

Chemical Name: 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid

 

Bexarotene | Retinoid X receptor agonist | Axon Medchem | Axon 1700 | SR 1147 - Targretin - Targret - LGD-1069

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

Nuclear Receptors - Retinoid X Receptor (RXR) (click)

 

Bexarotene | RXR agonist