Temsirolimus - CCI 779 | Torisel

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1699

CAS [162635-04-3]

MF C56H87NO16
MW 1030.29

Purity: 99%
Soluble in DMSO

Temsirolimus

Description

Specific mTOR inhibitor; a signaling protein that regulates cell growth and angiogenesis; a therapeutic for the treatment of advanced renal cell carcinoma (RCC), kidney cancer and other cancer types.

X Wan et al. CCI-779 Inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/HIF-1alpha/VEGF signaling. Neoplasia 2006, 8(5), 394–401.

D DelBufalo et al. Antiangiogenic potential of the mammalian target of rapamycin inhibitor temsirolimus. Cancer Res. 2006, 66(11), 5549–5554.

GV Thomas et al. Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer. Nature Medicine 2006, 12(1), 122–127.

mTOR inhibitor

Chemical name

42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate]-Rapamycin

Parent CAS No.

[162635-04-3]

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Size	Unit Price	Stock
10 mg	€95.00	In Stock
50 mg	€295.00	In Stock

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Temsirolimus - CCI 779 | Torisel

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Parent CAS No.

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Temsirolimus - CCI 779 | Torisel

Description

Chemical name

Parent CAS No.

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