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Digoxigenin bisdigitoxoside

CAS 5297-05-2

C35H54O11  MW 650.80

Purity: 98%

Soluble in DMSO to 100 mM

Ordering Information:

Cat. No. Axon 1695  

Qty1: 10 mg / €155  $202

Qty2: 50 mg / €555  $722

Qty3: on request

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Biological Activity:   A metabolite of Digoxin (Axon 1649)   Digoxin is a heart medication. Digoxin is also used as a standard control substance to test for p-glycoprotein inhibition. Recent studies show that digoxin acts as inhibitor of HIF-1α synthesis, reduces protein levels and thus slows tumor growth in mice.   References: online   U. Abshagen and N. Rietbrock. Metabolism of Digoxigenin, digoxigeninmonodigitoxoside and digoxigeninbisdigitoxoside in rats. NAUNYN-SCHMIEDEBERG's ARCH. PHARMACOL. 1973, 276(2), 157-166. [online]     Chemical Name: 3-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-[(2R,4S,5S,6R)-5-[(2S,4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-12,14-dihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

Digoxigenin bisdigitoxoside | matabolite of Digoxin | Axon Medchem | Axon 1695

Axon Ligands In The Field: