|
Biological Activity:
A specific androgen receptor antagonist or anti-androgen; RU 58841 has a dramatic effect on hair regrowth.
References:
N Obana et al. Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque. Endocrinology 1997, 138(1), 356-361. [online]
T Battmann et al. RU 58841, a new specific topical antiandrogen: A candidate of choice for the treatment of acne, androgenetic alopecia and hirsutism. J. Steroid Biochem. Mol. Biol. 1994, 48(1), 55-60. [online]
HI Pan et al. Evaluation of RU58841 as an anti-androgen in prostate PC3 cells and a topical anti-alopecia agent in the bald scalp of stumptailed macaques. Endocrine 1998, 9(1) 39-43. [online]
Chemical Name: 4-(1-(4-hydroxybutyl)-5,5-dimethyl-2,4-dioxopyrrolidin-3-yl)-2-(trifluoromethyl)benzonitrile
| 
