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MDL 201012

 

 

CAS 136722-45-7

136722-55-9 (HCl)

C19H25NO2  MW 299.41

Purity: 99%

Soluble in DMSO

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1679    Prime Source

 

Qty1: 10 mg / €115  $150

 

Qty2: 50 mg / €415  $540 

 

Qty3: on request

 

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or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Selective M3 muscarinic receptor antagonist; orally active antimuscarinic agent.

 

References: online

 

DL Reynolds et al. Determination of MDL 201,012 at femtomole/millilitre levels in human plasma by liquid chromatography with electrochemical detection
Biomed Chromatogr. 1992, 6(6), 295-9. [online] 

 

JP Carter et al. Analogues of oxybutynin. Synthesis and antimuscarinic and bladder activity of some substituted 7-amino-1-hydroxy-5-heptyn-2-ones and related compounds. J. Med. Chem. 1991, 34(10), 3065-74. [online]

 

 

Chemical Name: 1-cyclobutyl-7-(dimethylamino)-1-hydroxy-1-phenylhept-5-yn-2-one; aka CDHO

 

MDL 201012 | M3 antagonist | Axon Medchem | Axon 1679 | MDL201012 - CDHO

 

Axon LigandsTM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

MDL 201012 | M3 antagonist

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VU 0238429 | M5 PAM