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Asoprisnil

J867

 

CAS 199396-76-4

 C28H35NO4 MW 449.58

Purity: 98%

 

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1675   

 

Qty1: 5 mg (research sample) / €120  $156

 

Qty2: 25 mg (research sample) / €380  $494

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

A selective progesterone receptor (PR) modulator, tested for treatment of progesterone sensitive myomata.

 

References: online

 

D DeManno et al. Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy. Steroids 2003, 68 (10-13), 1019–1032. [online]

 

G Schubert et al. Discovery, chemistry, and reproductive pharmacology of asoprisnil and related 11beta-benzaldoxime substituted selective progesterone receptor modulators (SPRMs). Semin Reprod Med. 2005, 23(1), 58-73. [online]

 

 

 

Chemical Name: (E)-11R,13S,14S,17S)-17-methoxy-17-(methoxymethyl)-13-methyl-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)benzaldehyde oxime 

 

Asoprisnil | PR modulator | Axon Medchem | Axon 1675 | J867 

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

Nuclear Receptors - Progesterone Receptor (click)

 

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RU 486 | PR antagonist

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