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STF 083010

 

 

CAS 307543-71-1

C15H11NO3S2  MW 317.38

Purity: 99%

Soluble in DMSO >100 mM

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1670     Prime Source Promotion

 

Qty1: 10 mg (research sample) / €125  $163

 

Qty2: 50 mg (research sample) / €375  $488   

 

Qty3: on request contract research synthesis

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Specific IRE1 alpha endonuclease inhibitor without affecting its kinase activity; shows significant antimyeloma activity in human MM xenografts.

 

References:

 

I Papandreou et al. Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma. Blood 2011, 117, 1311-1314. [online] 

 

 

Chemical Name: (E)-N-((2-hydroxynaphthalen-1-yl)methylene)thiophene-2-sulfonamide

 

STF 083010 | IRE1 inhibitor | Axon Medchem | Axon 1670 | STF083010

Axon Ligands TM  - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

 

axonmedchem.com © 2011

 

Axon Ligands In The Field:

 

Irestatin 9389 | IRE1 inhibitor

STF 083010 | IRE1 inhibitor

 

 

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