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Danoprevir  - ITMN 191

RG7227 - R7227

 

CAS 850876-88-9

 C35H46FN5O9S MW 731.83 

Purity: 99% (optically pure)

 

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1669    Prime Source Promotion

 

Qty1: 2 mg (research sample) / 135  $189

 

Qty2: 5 mg (research sample) / €205  $306

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Potent and orally active inhibitor of hepatitis C virus (HCV) NS3/4A serine protease (replicon IC50: 1.6 nM)

 

References: online 1

 

EJ Gane et al. Antiviral activity, safety, and pharmacokinetics of danoprevir / ritonavir plus PEG-IFN α-2a/RBV in hepatitis C patients. J Hepatol. 2011 Feb 24. [Epub ahead of print]

 

 

Chemical Name:  

 

Danoprevir - ITMN 191 | HCV Protease inhibitor | Axon Medchem | Axon 1669 | ITMN191 - RG7227 - RG 7227 - R7227 - R 7227

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com © 2012

 

Axon Ligands in the field:

 

Rupintrivir | HRV 3C inhibitor

Atazanivir | Protease inhibitor

D-Atazanivir | Protease inhibitor

Danoprevir | HCV protease inh.

Nelfinavir | Protease inhibitor

Dapivirine | NNRT inhibitor