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SU 5402

 

 

CAS 215543-92-3

C17H16N2O3  MW 296.32

Purity: 99%

Soluble in DMSO 

Soluble in aq. NaOH (1eg.) 

 

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1667   Prime Source Promotion

 

Qty1: 1 mg€99  $129

Qty2: 2 mg / €149  $194

Qty3: 5 mg / €225  $293

 

Qty4: on request

 

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or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Fibroblast growth factor receptor (FGFR) inhibitor

 

References:

 

EK Grand et al. Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074. Leukemia 2004, 18, 962–966. [online]

 

Y Tanaka et al. FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. Nature 2005, 435(7039), 172-177. [online]

 

JL Paterson et al. Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma. Br. J. Haematol. 2004, 124(5), 595-603. [online]

 

Chemical Name: 3-(4-Methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid

 

SU 5402 | FGFR inhibitor | Axon Medchem | Axon 1667 | SU5402

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

PD 173074 | FGFR inhibitor

SU 5402 | FGFR inhibitor

 

 

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