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A 357300

C15H22ClN3O3S 

MW 359.87

Purity: 99% (optically pure)

Soluble in DMSO to 41 mM

Ordering Information:

Cat. No. Axon 1666     Prime Source

Qty1: 5 mg (research sample) / €125  $163

Promotion: 2 x 5 mg @ €180  $234

Qty2: 25 mg (research sample) / €425  $553

Promotion: 2 x 25 mg @ €640  $832

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

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Biological Activity:   Potent and reversible inhibitor of methionine aminopeptidase-2 (MetAP-2).   References:   J Wang et al. Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2. Cancer Res. 2003, 63(22), 7861-7869. [online] MJ Morowitz et al. Methionine aminopeptidase 2 inhibition is an effective treatment strategy for neuroblastoma in preclinical models. Clin. Cancer Res. 2005, 11(7), 2680-2685. [online]          Chemical Name: N'-[(2S,3R)-3-amino-2-hydroxy-5-propan-2-ylsulfanylpentanoyl]-3-chlorobenzohydrazide

A 357300 | MetAP-2 inhibitor | Axon Medchem | Axon 1666 | A357300