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S 9947

CAS 332378-43-5

C29H27N3O3  MW 465.54

Purity: 99%

Soluble in DMSO to 64 mM

Ordering Information:

Cat. No. Axon 1657

Qty1: 10 mg / €135  $176 

Qty2: 50 mg / €475  $618 

Qty3: on request

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Biological Activity:   Kv1.5 or IKur channel blocker, which suppresses both cloned (Kv1.5) and native (IKur) cardiac potassium current.   References:   A Bachmann et al. Characterization of a novel Kv1.5 channel blocker in Xenopus oocytes, CHO cells, human and rat cardiomyocytes. Naunyn Schmiedebergs Arch Pharmacol. 2001, 364(5), 472-478. [online]   K Knobloch et al. Electrophysiological and antiarrhythmic effects of the novel IKur channel blockers, S9947 and S20951, on left vs. right pig atrium in vivo in comparison with the IKr blockers dofetilide, azimilide, d,l-sotalol and ibutilide. Naunyn-Schmiedebergs Arch. Pharmacol. 2002, 366(5), 482-487. [online]      Chemical Name: 2'-(benzyloxycarbonylaminomethyl)biphenyl-2-carboxylic acid 2-(2-pyridyl)ethylamide

S 9947 | IKur channel blocker | Axon Medchem | Axon 1657 | S9947

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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