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GB 83 

CAS 1252806-86-2

C32H44N4O4  MW 548.72

Purity: 99% (optically pure)

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1622    Exclusive Promotion

Qty1: 1 mg (research sample) / €110  $143

Qty2: 5 mg (research sample) / inquire

Qty3: on request contract research synthesis

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Biological Activity:   Selective antagonist of human protease activated receptor 2 (PAR2) (IC50: 2 micromolar); reversibly inhibits PAR2 activation by both proteases and other PAR2 agonists.   References:   GD Barry et al. Novel agonist and antagonist for human protease activated receptor 2. J. Med. Chem. 2010, 53, 7428-7440. [online]     Chemical Name: N-((S)-3-cyclohexyl-1-((2S,3S)-1-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)-3-methyl-1-oxopentan-2-ylamino)-1-oxopropan-2-yl)isoxazole-5-carboxamide

GB 83 | PAR2 antagonist | Axon Medchem | Axon 1622 | GB83

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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