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XMD8-92

CAS 1234480-50-2 (free base)

C26H30N6O3.CF3CO2H MW 588.58

Purity: 99%

Soluble in Water and DMSO

Ordering Information:

Cat. No. Axon 1621    2012 Promoion 

Qty1: 2 mg (research sample) / €90  $117

Qty2: 5 mg (research sample) / €125  $163

Promotion: 2 x 5 mg @ €180  $234

Qty3: 25 mg (research sample) / €425  $553

Promotion: 2 x 25 mg @ €680  $884

Qty4: on request

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or by fax to: +31-50-3600390.

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Biological Activity:   Potent and selective inhibitor of big MAP kinase 1 (BMK1/ERK5).   References: online   Q. Yang et al. Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein. Cancer Cell, 2010, 18(3), 258-267. [online]   Q Yang and JD Lee. Targeting the BMK1 MAP Kinase Pathway in Cancer Therapy. Clin. Cancer Res. 2011, 17, 3527-3532. [online]     Chemical Name: 2-(2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one trifluoroacetate

XMD8-92 | BMK1 inhibitor | Axon Medchem | Axon 1621 | XMD 8-92

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In This Field:

FR 180204 | ERK inhibitor