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NVP 231

 

 

CAS 362003-83-6

C25H25N3O2S MW 431.55

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1600    Prime Source

 

Qty1:  5 mg / 85  $111

Promotion: 2 x 5 mg @ 120  $156

Qty2: 25 mg / 285  $371

Promotion: 2 x 25 mg @ 420  $546

Qty3: on request

 

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Biological Activity:

 

Potent, specific and reversible ceramide kinase (CerK) inhibitor with activity in low nanomolar range.

 

References:

 

C Graf et al. Targeting ceramide metabolism with a potent and specific ceramide kinase inhibitor. Mol. Pharmacol. 2008, 74(4), 925-932. [online]


C Graf et al. A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides. Anal. Biochem. 2009, 384(1), 166-169. [online]

 

 

Chemical Name: N-[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide

 

NVP 231 | CerK inhibitor | Axon Medchem | Axon 1600 | NVP231

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

NVP 231 | CerK inhibitor

 

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