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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

PPP hydrochloride

 

 

CAS 21602-56-2

C19H21N.HCl  MW 239.78

Purity: 99%

Water-soluble 

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1595    

 

Qty1: 10 mg / €105  $137

 

Qty2: 50 mg / €315  $410

 

Qty3: on request

 

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Biological Activity:

 

Selective inacticvator of human cytochrome P450 2B6 (CYP2B6).

 

References:

 

RL Walsky and RS Obach. A Comparison of 2-Phenyl-2-(1-piperidinyl)propane (PPP), 1,1′,1″-Phosphinothioylidynetrisaziridine (ThioTEPA), Clopidogrel, and Ticlopidine as Selective Inactivators of Human Cytochrome P450 2B6. 

Drug Metab. Dsipos. (DMD). 2007, 35(11), 2053-2059. [online]

 

J Chun et al. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane. Drug Metab Dispos. 2000, 28(8), 905-911. [online]

 

 

Chemical Name: 2-phenyl-2-(1-piperidinyl)propane

 

PPP | CYP2B6 inhibitor| Axon Medchem | Axon 1595

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Axon Ligands In The Field:

 

PPP | CYP2B6 inhibitor 

Tienilic acid | CYP2C9 inhibitor