Dopaminergic stabilizer (Ki values 17550 nM and 7521 for D2(low) and D2(high), respectively) that state-dependently stabilizes psychomotor activity by the dual actions of functional dopamine D2 receptor antagonism and strengthening of cortical glutamate functions in various settings of perturbed neurotransmission. Useful for ameliorating several neurological and psychiatric disorders, including Huntington's disease.

KEYWORDS: Pridopidine hydrochloride | supplier | Dopaminergic stabilizer | ACR16 hydrochloride | ACR16 HCl | Huntexil | CAS [882737-42-0] | [346688-38-8] | Dopamine | D2 | Stabilizer | GPCR | Huntington's disease | psychomotor activity | antagonism | cortical glutamate | perturbed neurotransmission | psychiatric disorders