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AG 7088  - Rupintrivir

Ruprintrivir

CAS 223537-30-2

 C31H39FN4O7 MW 598.66 

Purity: >98% (optically pure)

Ordering Information:

Cat. No. Axon 1571    Prime Source Promotion

(*limited amount in stock)

Qty1: 1 mg (research sample) / €135  $176

Qty2: 5 mg (research sample) / €405  $527

Qty3: on request contract research synthesis

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Biological Activity:   An irreversible human rhinovirus (HRV) 3C protease inhibitor   References:   G Witherell. AG-7088 Pfizer. Curr. Opin. Investig. Drugs. 2000, 1(3), 297-302. [online]   AG-7088. Drugs Fut. 2000, 25, 1, 9   ST Worland et al. Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics. J. Med. Chem. 1999, 42,(7), 1203.   SL Binford et al. In Vitro Resistance Study of Rupintrivir, a Novel Inhibitor of Human Rhinovirus 3C Protease. ANTIMICROB. AGENTS CHEMOTHER. 2007, 51(12), 4366–4373.     Chemical Name: 4(S)-[2(R)-(4-Fluorobenzyl)-6-methyl-5(S)-(5-methylisoxazol-3-ylcarboxamido)-4-oxoheptanamido]-5-[2-oxo-3(S)-pyrrolidinyl]-2(E)-pentenoic acid ethyl ester

AG 7088 | HRV 3C Protease inhibitor | Axon Medchem | Axon 1571 | Rupintrivir - Ruprintrivir

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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