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PS 1145

 

 

CAS 431898-65-6  

C17H11ClN4O  MW 322.76

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1568     Prime Source

 

Qty1: 5 mg / €105  $137

 

Qty2: 25 mg / €350  $455

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

A highly specific IKB kinase (IKK) inhibitor; efficiently inhibits both basal and induced NF-kB activity in PC cells.

 

References:

 

A Yemelyanov et al. Effects of IKK inhibitor PS1145 on NF-kB function, proliferation, apoptosis and invasion activity in prostate carcinoma cells
Oncogene 2006, 25, 387–398. [online]

 

 

 

Chemical Name: N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide

 

PS 1145 | IKK inhibitor | Axon Medchem | Axon 1568 | PS1145 | MLN1145

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands in the field:

 

BMS 345541 | IKK inhibitor

PHA 408 | IKK-2 inhibitor

PS 1145 | IKK inhibitor

 

 

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