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Biological Activity:
A highly specific IKB kinase (IKK) inhibitor; efficiently inhibits both basal and induced NF-kB activity in PC cells.
References:
A Yemelyanov et al. Effects of IKK inhibitor PS1145 on NF-kB function, proliferation, apoptosis and invasion activity in prostate carcinoma cells Oncogene 2006, 25, 387–398. [online]
Chemical Name: N-(6-Chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide
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| PS 1145 | IKK inhibitor | Axon Medchem | Axon 1568 | PS1145 | MLN1145 |
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Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.
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Axon Ligands in the field:
BMS 345541 | IKK inhibitor
PHA 408 | IKK-2 inhibitor
PS 1145 | IKK inhibitor
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