Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

Posaconazole

SCH 56592 - Noxafil

CAS 171228-49-2

C37H42F2N8O4  MW 700.8

Purity: 99% (optically pure)

Ordering Information:

Cat. No. Axon 1557    Prime Source

Qty1: 5 mg (research sample) / €165  $215

Promotion: 2 x 5 mg @ €240  $312

Qty2: 25 mg (research sample) / €625  $813

Promotion: 2 x 25 mg @ €880  $1144

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Contact us for payment and tech support.

Biological Activity:   A triazole antifungal drug; the most potent sterol biosynthesis inhibitor and antiproliferative agent ever tested against both proliferative stages of T. cruzi.   References: online   JA Urbina et al. Antiproliferative Effects and Mechanism of Action of SCH 56592 against Trypanosoma (Schizotrypanum)cruzi: In Vitro and In Vivo Studies. Antimicrob. Agents Chemother. 1998, 42(7), 1771-1777. [online]   DS Schiller and HB Fung. Posaconazole: an extended-spectrum triazole antifungal agent. Clin Ther 2007, 29(9), 1862–86. [online]   EJ Rachwalski et al. Posaconazole: an oral triazole with an extended spectrum of activity. Ann Pharmacother 2008, 42 (10): 1429–38. [online]     Chemical Name: D-threo-Pentitol, 2,5-anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-

Posaconazole | Antifungal agent | Axon Medchem | Axon 1557 | Noxafil - SCH 56592

axonmedchem.com © 2012

Axon Ligands ^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.