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CNF 2024 - BIIB 021

 

 

CAS 848695-25-0

C14H15ClN6O  MW 318.77

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1543     Prime Source

 

Qty1: 5 mg (research sample) / €95  $124

 

Qty2: 25 mg (research sample) / €285  $371

 

Qty4: on request

 

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Biological Activity:

 

Oral inhibitor of heat shorck protein 90 (Hsp90) under clinical development.

 

References:

 

B Böll et al. Heat Shock Protein 90 Inhibitor BIIB021 (CNF2024) Depletes NF-κB and Sensitizes Hodgkin's Lymphoma Cells for Natural Killer Cell–Mediated Cytotoxicity. Clin. Cancer Res. 2009, 15(16), 5108–16. [online]

 

T Taldone et al. Targeting Hsp90: small-molecule inhibitors and their clinical development. Cur. Opin. Pharmacol. 2008, 8(4), 370-374. [online]

 

 

Chemical Name:

 

CNF 2024 - BIIB 021 | Hsp90 inhibitor | Axon Medchem | Axon 1543 | CNF2024 - BIIB021

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

CNF 2024 | Hsp90 inhibitor

NVP-AUY922 | Hsp90 inhibitor

 

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