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Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

 

 

 

  

CP 226269

 

 

CAS 220941-93-5

C18H19FN4  MW 310.38

Purity: 99 %

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1521    Prime Source

 

Qty1: 5 mg (research sample) / €95  $124

Promotion: 2 x 5 mg @ 140  $182

Qty2: 25 mg (research sample) / €285  $371

Promotion: 2 x 25 mg @ 440  $572

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

Contact us for payment and tech support.

 

Biological Activity:

 

Selective dopamine D4 agonist; highly recommended tool for researching the role of D4 receptor in the brain.

 

References:

 

A Sharma et al. D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia. Mol. Psychiatry 1999, 4(3), 235–46. [online]


AM Basso et al. Antidepressant-like effect of D2/3 receptor-, but not D4 receptor-activation in the rat forced swim test. Neuropsychopharmacol. 2005, 30(7), 1257–68. [online]

 

 

 

Chemical Name: 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole

 

CP 226269 | D4 agonist | Axon Medchem | Axon 1521 | CP226269

axonmedchem.com © 2011

 

Axon Ligands in The Field:

ABT 724 | D4 agonist

CP 226269 | D4 agonist

 

Other Dopamine Ligands: e.g.

7-hydroxy-DPAT | D3 agonist

(R)-(+)-7-OH-DPAT | D3 agonist

(±)-PD 128907 | D3 agonist

(+)-PD 128907 | D3 agonist

ST 198 | D3 antagonist

U 99194 | D3 antagonist

GR 103691 | D3 antagonist

 

5-hydroxy-DPAT | D2 agonist

(S) 5-hydroxy-DPAT | D2 agonist

R(-)-NPA | D2 agonist

RU 24213 | D2 agonist

(+)-PHNO | D2 agonist

PPHT - N-0434 | D2 agonist

Molindone | D2 antagonist

ST 148 | D2 antagonist

 

S-(+)-Dinapsoline | D1 agonist

NNC 776 | D1 antagonist

SKF-83566 | D1 antagonist

N-0426 | DA agonist

N 0734 | DA agonist  

Rotigotine - N-0437 | DA agonist

(-)-Rotigotine | DA agonist

Piribedil | Dopamine agonist

TL 99 | Dopamine agonist

TL 102 | Dopamine agonist

TL 232 | Dopamine agonist