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Dorzolamide hydrochloride

 

 

CAS 130693-82-2

C10H16N2O4S3.HCl  MW 360.90

Purity: 99%

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1517           Prime Source

 

Qty1: 10 mg (research sample) / €125  $163

 

Qty2: 50 mg (research sample) / €325  $423

 

Qty3: on request

 

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Biological Activity:

 

A carbonic anhydrase inhibitor; antiglucoma agent, used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.

 

References: online

 

C Plummer et al. Comparison of the effects of topical administration of a fixed combination of dorzolamide-timolol to monotherapy with timolol or dorzolamide on IOP, pupil size, and heart rate in glaucomatous dogs. Vet. Ophthalmol. 2006, 9(4), 245–249.

 

S Grover et al. Topical dorzolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa. Am. J. Ophthalmol. 2006, 141(5), 850–858.

 

Chemical Name: (4S,6S)-2-ethylamino-4-methyl-5,5-dioxo-5λ6,7-dithiabicyclo[4.3.0]nona-8,10-diene-8-sulfonamide hydrochloride

 

Dorzolamide | Carbonic anhydrase inhibitor | Axon Medchem | Axon 1517 | Trusopt 

Axon Ligands TM    

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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