|
Biological Activity:
A carbonic anhydrase inhibitor; antiglucoma agent, used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension.
References: online
C Plummer et al. Comparison of the effects of topical administration of a fixed combination of dorzolamide-timolol to monotherapy with timolol or dorzolamide on IOP, pupil size, and heart rate in glaucomatous dogs. Vet. Ophthalmol. 2006, 9(4), 245–249.
S Grover et al. Topical dorzolamide for the treatment of cystoid macular edema in patients with retinitis pigmentosa. Am. J. Ophthalmol. 2006, 141(5), 850–858.
Chemical Name: (4S,6S)-2-ethylamino-4-methyl-5,5-dioxo-5λ6,7-dithiabicyclo[4.3.0]nona-8,10-diene-8-sulfonamide hydrochloride
|