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ONO 8711 dicyclohexyl amine salt

CAS 216158-34-8

C22H30ClNO4S.C12H23N

 MW 621.33  Purity: >98%

Ordering Information:

Cat. No. Axon 1512   Prime Source

Qty1: 5 mg / €125  $163

Qty2: 25 mg / €425  $553

Qty3: on request

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Biological Activity:   A selective prostaglandin E (PGE) receptor EP1 antagonist with chemoproventive effects.   References:   T Kawamori et al. Chemopreventive effects of ONO-8711, a selective prostaglandin E receptor EP1 antagonist, on breast cancer development. Carcinogenesis. 2001, 22(12), 2001-2004. [online]   H Makita et al. A prostaglandin E2 receptor subtype EP1-selective antagonist, ONO-8711, suppresses 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Carcinogenesis 2007, 28(3), 677-684. [online]     Chemical Name: 6-[(2S,3S)-3-(4-chloro-2-methylphenylsulfonyl-amnomethyl)-bicyclo[2.2.2.] octan-2-yl]-5Z-hexenoic acid, dicyclohexyl amine [1:1]

ONO 8711 | EP1 antagonist | Axon Medchem | Axon 1512 | ONO8711

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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