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ABT 239 tartrate

CAS 460748-71-4

460746-46-7 (parent)

C22H22N2O.C4H6O6 

MW 480.52 

Purity: 99% (optically pure)

Ordering Information:

Cat. No. Axon 1510    Prime Source

Qty1: 5 mg (research sample) / €139  $181

* limited stock for promotion

Qty2: on request contract research synthesis

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Biological Activity:   Potent and selective histamine H3 receptor antagonist or inverse agonist; a highly recommended tool for animal research into H3 antagonist / inverse agonist.   References: online   TA Esbenshade et al. Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties. J. Pharmacol. Exp. Ther. 2005, 313(1), 165–75. [online]   GB Fox et al. Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist. J. Pharmacol. Exp. Ther. 2005, 313 (1): 176–90. [online]   M Cowart et al. 4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention". J. Med. Chem. 2005, 48 (1), 38–55. [online]     Chemical Name: 4-(2-{2-[(2R)-2-Methylpyrrolidin-1-yl]ethyl}-benzofuran-5-yl)benzonitrile

ABT 239 | H3 antagonist | Axon Mechem | Axon 1510 | ABT239

Axon Ligands TM Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Histamine Receptor (HR) Ligands available: e.g.

ABT 239 | H3 antagonist