Bifeprunox | Atypical antipsychotic | Axon Ligands | Axon 1508

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Bifeprunox mesylate - DU 127090

CAS 350992-13-1 (mesylate)

350992-10-8 (free base)

C24H23N3O2.CH4O3S

MW 481.58 Purity: 99%

Ordering Information:

Cat. No. Axon 1508

Qty1: 10 mg / 120 $156

Qty2: 50 mg / 360 $468

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Dopamine D2 and 5-HT1A partial agonist in development as a potential treatment for schizophrenia and other psychotic indications; Pharmacoloy profile maskes it an atypical antipsychotic and a new approach for the treatment of schizophrenia.

References: online

DE Casey et al. Efficacy and safety of bifeprunox in patients with an acute exacerbation of schizophrenia: results from a randomized, double-blind, placebo-controlled, multicenter, dose-finding study. Psychopharmacology 2008, 200, 317-331.

L Bardin et al. Pharmacological profiles in rats of novel antipsychotics with combined dopamine D2/serotonin 5-HT1A activity: comparison with typical and atypical conventional antipsychotics. Behav. Pharmacol. 2007, 18(2), 10318.

Drugs Fut. 2006, 31(3), 268.

Chemical Name: 7-[4-(biphenyl-3-ylmethyl)piperazin-1-yl]-1,3-benzoxazol-2(3H)-one methanesulfonate (1:1)

Bifeprunox | Atypical antipsychotic | Axon Medchem | Axon 1508 | DU 127090 - DU127090

Axon Ligands ^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.