Asenapine | Atypical antipsychotic | Axon Ligands | Axon Medchem

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Asenapine maleate - Org 5222

CAS 85650-56-2 (maleate)

65576-45-6 (free base)

C17H16ClNO.C4H4O4

MW 401.84 Purity: 99%

Ordering Information:

Cat. No. Axon 1503 Prime Source

Qty1: 10 mg / 95 $124

Qty2: 50 mg / 285 $371

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

An atypical antipsychotic for the treatment of schizophrenia and acute mania associated with bipolar disorder; Displays high affinity antagonistic activities at many receptors, including dopamine (D1-4) and serotonin (5-HT1-7) receptor subtypes. However, it has much lower affinity (pKi < 5) for the muscarinic acetylcholine receptors.

References: online

M Shahid et al. Asenapine: a novel psychopharmacologic agent with a unique human receptor signature. J. Psychopharmacol. 2009, 23(1), 6573. [abstract]

Chemical Name: (3aRS,12bRS)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole (2Z)-2-butenedioate (1:1)

Asenapine | Atypical antipsychotic | Axon Medchem | Axon 1503 | Safaris - Org 5222 - Org5222

Axon Ligands ^TM- Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.