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Flibanserin

BIMT 17

CAS 167933-07-5

C20H21F3N4O  MW 390.40

Purity: 99%

Ordering Information:

Cat. No. Axon 1499      Prime Source Promotion

Qty1: 10 mg (research sample) / €95  $124

Qty2: 50 mg (research sample) / €285  $371

Qty3: on request

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Biological Activity:   A 5-HT1A receptor full agonist with 5-HT2A receptor antagonistic activity; It was initially investigated as an potential antidepressant, however, it is currently under clinical trial for the potential treatment of female sexual dysfunction.    References: online   E Jolly et al. Design of Phase III pivotal trials of flibanserin in female Hypoactive Sexual Desire Disorder (HSDD). Sexologies. 2008, 17, Supplement 1, S133-S134. [abstract]   Flibanserin. WHO Drug Information 1997; 11/1: 40. IDdb, 25 Jan 2007.    F Borsini et al. Pharmacology of flibanserin. CNS Drug Rev. 2002, 8 (2), 117–142. [abstract]           Chemical Name: 1-[2-[4-(3-trifluoromethyl phenyl) piperazin-1-yl] ethyl] benzimidazol-[1H]-2-one

Flibanserin | 5-HT1A agonist and 5-HT2A antagonist | Axon Medchem | Axon 1499 | BIMT 17

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Axon 5-HT1A Lgands: e.g.

p-MPPF

p-MPPI

(-)-NPPCC

S 14506

WAY 100135

WAY 100635

(+/-)-LY 426965

S(+)-426965

Desmethyl S 14506

DWAY 100165

FCWAY

8-OH-DPAT

R(+)-8-OH-DPAT

U 92016A

Axon Ligands ^TM

Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.