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Axon 1495
CAS [1080622-86-1]
MF C17H15N7O2MW 349.35
Specific ATM inhibitor; no inhibition of PI3K or PI3K-like protein kinases (PIKK) or Abl kinase in cells; does inhibit cellular ATM-dependent phosphorylation events and disruption of ATM function resulted in characteristic cell cycle checkpoint defects; highly recommended tool to rapidly and reversibly regulate ATM activity.
KEYWORDS: CP 466722 | supplier | ATM inhibitor | CP466722 | CP-466722 | CAS [1080622-86-1] | DNA-RNA | DNA damage | cell cycle | checkpoint | ataxia-telangiectasia | radiosensitization
List of publications using CP 466722 (Axon 1495) purchased from Axon Medchem
2-(6,7-Dimethoxy-quinazolin-4-yl)-5-pyridin-2-yl-2H-[1,2,4]triazol-3-ylamine
[1080622-86-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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