Agomelatine

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1492

CAS [138112-76-2]

MF C15H17NO2
MW 243.30

Purity: 99%
Soluble in DMSO

Agomelatine

Description

Potent melatonin agonist; first melatonin antidepressant; also known as a norepinephrine dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor

SA Montgomery. Major depressive disorders: clinical efficacy and tolerability of agomelatine, a new melatonergic agonist. Eur. Neuropsychopharmacol, 2006, 16, suppl 5, S633-S638.

MJ Millan et al. The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-HT2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways. J. Pharmacol. Exp. Ther. 2003, 306 (3), 954–954.

Melatonin agonist; 5-HT2C antagonist

Chemical name

N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide

Parent CAS No.

[138112-76-2]

Order

Size	Unit Price	Stock
10 mg	€75.00	In Stock
50 mg	€175.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description
1335	AH 001	Melatonin agonist	€80.00
1336	AH 002	Melatonin agonist	€80.00
1350	Luzindole	Melatonin antagonist	€95.00
1351	DH 97	Melatonin (MT2) antagonist	€95.00
2889	VA012	Positive allosteric modulator (PAM) of 5-HT2C receptor	€105.00

Customer Support

Customer Services

About Axon Medchem

Contact Us

Agomelatine

Description

Chemical name

Parent CAS No.

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Customer Support

Customer Services

About Axon Medchem

Contact Us

Agomelatine

Description

Chemical name

Parent CAS No.

Related Products

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Send us a message

Contact Us