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Anacardic acid A

6- Pentadecylsalicylic acid

CAS 16611-84-0

C22H36O3  MW 348.53

Purity: >98%

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1490

Qty1: 10 mg / €60  $78

Qty2: 50 mg / €240  $312

Qty3: on request

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Biological Activity:   A cell-permeable, non-competitive inhibitor of histone acetyl transferase (HAT).   References:   K. Balasubramanyam, et al. Small molecule modulators of histone acetyltransferase p300. J. Biol. Chem. 2003, 278, 19134. Y. Sun et al. Inhibition of histone acetyltransferase activity by anacardic acid sensitizes tumor cells to ionizing radiation. FEBS Lett. 2006, 580, 4353.   B Sung et al. Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-kappaB-regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-kappaBalpha kinase, leading to potentiation of apoptosis. Blood. 2008, 111(10), 4880-91. [abstract]       Chemical Name: 2-Hydroxy-6-pentadecyl-benzoic acid; Hydroginkgolic acid

Anacardic acid A | HAT inhibitor | Axon Medchem | Axon 1490

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Axon Ligands In The Field: