Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

Fingolimod  - FTY 720

CAS 162359-56-0

C19H33NO2.HCl  MW 343.93

Purity: >98%

Ordering Information:

Cat. No. Axon 1485

Qty1: 10 mg / €75  $98

Qty2: 50 mg / €175  $228

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Contact us for payment and tech support.

Biological Activity:   A sphingosine-1-phosphate receptor 1 modulator; immunosuppressant.   References: online   EV Berdyshev et al. FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells. J. Biol. Chem. 2009, 284(9), 5467–77.   KK Dev et al. Brain sphingosine-1-phosphate receptors: implication for FTY720 in the treatment of multiple sclerosis. Pharmacol. Ther. 2008, 117, 77-93.   K Chiba et al. Role of sphingosine 1-phosphate receptor type 1 in lymphocyte egress from secondary lymphoid tissues and thymus. Cell Mol. Immunol. 2006, 3, 11-19.    U Kunzendorf et al. FTY720—the first compound of a new promising class of immunosuppressive drugs. Nephrol. Dial. Transplant. 2004, 19, 1677-1681.     Chemical Name: 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol hydrochloride

Fingolimod - FTY 720 | S1P agonist | Axon Medchem | Axon 1485 | FTY720

axonmedchem.com © 2011

Axon Ligands in the Field: