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VU 0152100

VU 152100

CAS 409351-28-6 

C18H19N3O2S MW 341.43

Purity: 99%

Ordering Information:

Cat. No. Axon 1483     2012 Promotion

Qty1: 5 mg / €95  $124

Promotion: 2 x 5 mg @ €140  $182

Qty2: 25 mg / €332  $432

Promotion: 2 x 25 mg @ €500  $650

Qty3: on request

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Biological Activity:   Positive allosteric modulator of M4 muscarinic acetylcholine receptor (mAChR)   References:   AE Brady et al. Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Ratss. J. Pharmacol. Exp. Ther. 2008, 327(3),  941–953. [abstract]   CM Jones. M4 Positive Allosteric Modulators For The Treatment Of Schizophrenia. Grant 1R01MH086601-01 from National Institute Of Mental Health. [abstract]   P Jeffrey Conn et al. Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders. Trends in Pharmacological Sciences 2009, 30(3), 148-155. [abstract]     Chemical Name: 3-amino-N-(4-methoxybenzyl)-4,6-dimethylthieno[2,3-b]pyridine carboxamide

VU 0152100 | PAM of M4 mAChR | Axon Medchem | Axon 1483 | VU0152100 - VU152100 - VU 152100

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

Zamifenacin | M3 antagonist