Axon Ligands (TM) - alphabetic: [A] [B] [C] [D] [E] [F] [G] [H] [I] [J] [K] [L] [M] [N] [O] [P] [Q] [R] [S] [T] [U] [V] [W] [X] [Y] [Z]

Parogrelil

free base of NT 702 - NM 702

CAS 139145-27-0

C19H18BrClN4O2  MW 449.73

Purity: 99%

Ordering Information:

Cat. No. Axon 1482      Prime Source

Qty1:  5 mg (research sample) / €125  $163

Qty2: 25 mg (research sample) / €425  $553

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Contact us for payment and tech support.

Biological Activity:   Selective and potent PDE III (PDE3) inhibitor; a new type of agent with both a bronchodilating and an anti-inflammatory effect.   References:   M Hori et al. NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase 3 inhibitor, suppress the asthmatic response in guinea pigs, with both bronchodilating and anti-inflammatory effects. Eur. J. Pharmacol. 2009, 618(1-3), 63-69. [abstract]   N Ishiwata. NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase inhibitor, improves reduced walking distance and lowered hindlimb plantar surface temperature in a rat experimental intermittent claudication model. Life Sci. 2007, 81(12), 970-978. [abstract]     Chemical Name: 4-Bromo-6-[3-(4-chlorophenyl)propoxy]-5-[(3-pyridinylmethyl)amino]-3(2H)-pyridazinone

Parogrelil | PDE3 inhibitor | Axon Medchem | Axon 1482

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.