PLX 4720 | B-Raf inhibitor | Axon Ligands

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PLX 4720

CAS 918505-84-7

C17H14ClF2N3O3S

MW 413.83

Purity: 99%

Soluble in DMSO

Ordering Information:

Cat. No. Axon 1474 Prime Source

Qty1: 2 mg (research sample) / 90 $117

Qty2: 5 mg (research sample) / 125 $163

Promotion: 2 x 5 mg @ 180 $234

Qty3: 25 mg (research sample) / 425 $553

Promotion: 2 x 25 mg @ 600 $780

Qty4: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Selective inhibitor of protein kinase, targeting B-Raf (V600E).

References:

J Tsai et al. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci USA. 2008, 105(8), 3041-3046. [online]

Chemical Name: Propane-1-sulfonic acid [3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl]-amide

PLX 4720 | B-Raf inhibitor | Axon Medchem | Axon 1474 | PLX4720

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

axonmedchem.com Š 2012

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