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Tenilsetam

PAS 997 - CAS 997 - HR 029

CAS 86696-86-8

 C8H10N2OS MW 

Purity: 99 %

Ordering Information:

Cat. No. Axon 1470  

Qty1: 10 mg / €115  $150

Qty2: 50 mg / €315  $410

Qty3: on request

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Biological Activity:   Endonuclease modulator; a nootropic agent and advanced glycation end product (AGE) inhibitor having potential for Alzheimer's disease (AD) treatment. Preclinical studies on diabetic rats suggested that tenilsetam may be beneficial in the inhibition of diabetic retinopathy, without amelioration of pericyte loss.   References:   G Munch et al. The cognition-enhancing drug tenilsetam is an inhibitor of protein crosslinking by advance glycosylation. J. Neural. Transm. Sect. 1994, 8(3), 193-208. [abstract]   TJ Roesler et al. Advanced glycation end product (AGE) inhibition as a possible pharmacotherapeutic strategy in the treatment of Alzheimer's disease. Drugs Fut. 1999, 24(4), 411. [online]   IDdb, 24 May 2002.     Chemical Name: (+/-)-3-(2-thienyl)piperazin-2-one

Tenilsetam | AGE inhibitor | Axon Medchem | Axon 1470 |

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Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.