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MF C24H23FN4O3MW 434,46
Highly potent, oral and selective inhibitor of poly(ADP-ribose) polymerase (PARP); with IC50 = 5nM (PARP-1) and 1 nM (PARP-2). It blocks enzymes that repair DNA damage caused by cancer treatments such as radiation and drugs.
KEYWORDS: AZD 2281 | supplier | PARP inhibitor | Olaparib | KU 0059436 | AZD2281 | KU0059436 | AZD-2281 | KU-0059436 | CAS [763113-22-0] | DNA-RNA | poly-(ADP-ribose) polymerase | PARP-1 | PARP-2 | DNA damage | double strand break | DSB | CHK
List of publications using AZD 2281 (Axon 1464) purchased from Axon Medchem
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
Download the Axon Ligands™ catalogue Spring 2017 Edition
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