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Biological Activity:
5-HT2 and dopamine D2 antagonist with high affinity for 5-HT7 receptors; an atypical antipsychotic in the treatment of psychotic disorders with negative and positive symptomatology.
References: online
Leysen et al. Biochemical profile of risperidone, a new antipsychotic. J. Pharmacol. Exp. Ther. 1988, 247, 661.
Stathis et al. Risperidone: a novel antipsychotic with many "atypical" properties. Psychopharmacol. 1996, 127, 181.
A Szarfman et al. Atypical antipsychotics and pituitary tumors: a pharmacovigilance study. Pharmacotherapy 2006, 26(6), 748–58. [abstract]
Chemical Name: 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl] ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyri midin-4-one
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