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Dimebon

Dimebolin dihydrochloride

CAS 3613-73-8

 C21H27N3Cl2  MW 355.91 

Purity: 99 %

Ordering Information:

Cat. No. Axon 1445    

Qty1: 5 mg / €95  $124

Qty2: 25 mg / €285  $371

Qty3: on request

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Biological Activity:   An antihistamine drug; recent focus on it as potential neuroprotectant and nootropic, hence an Alzheimer's treatment; multiple mechanisms of action, including inhibiting L-type calcium channels, blocking the action of neurotoxic beta-amyloid proteins; and modulating the action of AMPA and NMDA glutamate receptors etc.   References: online   DJ DeNoon, Dimebon Shines as Alzheimer's Therapy. WebMD Health News. July 30, 2008. [online]   RS Doody et al. Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study. Lancet. 2008, 372(9634):207-15. [abstract]        Chemical Name: 2,3,4,5-Tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)ethyl)-1H-pyrido(4,3-b)indole dihydrochloride

Dimebon | Neuroprotectant | Axon Medchem | Axon 1445 | Dimebolin dihydrochloride

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Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.