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Lacosamide - SPM 927 - Erlosamide

CAS 175481-36-4

 C11H18N2O3 MW 250.29 

Purity: 99 % (optically pure)

Ordering Information:

Cat. No. Axon 1444    

Qty1: 10 mg (research sample) / €105  $137

Qty2: 50 mg (research sample) / €265  $345

Qty3: on request

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Biological Activity:   Lacosamide acts by enhancing slow inactivation of voltage gated sodium channels; a medication for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain.    References: online   AC Errington et al. The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels. Molecular pharmacology 2008, 73 (1), 157–69. [online]   AC Errington et al. Seeking a mechanism of action for the novel anticonvulsant lacosamide. Neuropharmacology 2006, 50 (8), 1016–1029. [online]   E Ben-Menachem et al. Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial-onset seizures. Epilepsia 2007, 48 (7), 1308–1317. [online]   RL Rauck et al. Lacosamide in painful diabetic peripheral neuropathy: a phase 2 double-blind placebo-controlled study. Clin J Pain 2007, 23 (2), 150–158. [online]     Chemical Name: (2R)-2-(acetylamino)-N-benzyl-3-methoxy-propionamide

Lacosamide | Anticonvulsant | Axon Medchem | Axon 1442

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Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.