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Genipin

CAS 6902-77-8

 C11H14O5  MW 226.23

Purity: 99 % (optically pure)

Ordering Information:

Cat. No. Axon 1443    

Qty1: 10 mg / €55  $72

Qty1: 50 mg / €115  $150

Qty3: on request contract research synthesis

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Biological Activity:   Active medication to relieve the symptoms of type 2 diabetes. Genipin stimulates insulin secretion in UCP2-dependent manner (Uncoupling protein 2). Genipin is a protein, collagen, gelatin, and chitosan cross-linker   References: online   LE Parton et al., Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired by obesity. Nature 2007, 449, 228-233.    C Zhang et al., Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity- and high glucose-induced B cell dysfunction in isolated pancreatic islets. Cell Metab. 2006, 3, 417-427.   Chemical Name: (1R,4aS,7aS)-1-Hydroxy-7-hydroxymethyl-1,4a,5,7a-tetrahydro-cyclopenta[c]pyran-4-carboxylic acid methyl ester

Genipin | Protein cross-linker | Axon Medchem | Axon 1443

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Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.