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HU-308

 

 

CAS 256934-39-1 

C27H42O3 MW 414.62 

 Purity: >98% (optically pure)

 

 

 

 

Ordering Information:

 

Cat. No. Axon 1440    Prime Source

 

Qty1: 5 mg / €115  $150

 

Qty2: 25 mg / €460  $598

 

Qty3: on request

 

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

 

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Biological Activity:

 

Potent cannabinoid agonist specific at CB2. It has analgesic effects, promotes proliferation of neural stem cells, and protects both liver and blood vessel tissues against oxidative stress via inhibition of TNF-α.

 

References: online 1

 

L Hanus et al. HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor. Proc. Natl. Acad. of Sci. USA. 1999, 96(25), 14228-33. [abstract]

 

CJ LaBuda et al. Cannabinoid CB2 receptor agonist activity in the hindpaw incision model of postoperative pain. Eur. J. Pharmacol. 2005, 527(1-3), 172-4. [abstract]

 

Baker et al. Cannabinoids control spasticity and tremor in a multiple sclerosis model. Nature 2000, 404, 84. 

 

 

Chemical Name: [(1R,2R,5R)-2-[2,6-dimethoxy-4-(2-methyloctan-2-yl)phenyl]-7,7-dimethyl-4-bicyclo[3.1.1]hept-3-enyl] methanol

 

HU-308 | CB2 agonist | Axon Medchem | Axon 1440 | HU308

 

Axon Ligands TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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Axon Ligands In The Field:

 

Abn-CBD | Axon 1235

Cannabidiol - CBD | Axon 1234

HU-308 | CB2 agonist

Iodopravadoline | CB antagonist

JWH 018 | CB2 agonist

JWH 073 | CB2 agonist 

JWH 133 | CB2 agonist

JWH 250 | CB agonist

Pravadoline | CB agonist

AM 251 | CB1 antagonist

AM 281 | CB1 antagonist

MK 0364 | CB1 inverse agonist

PSNCBAM-1 | CB1 antagonist

SR 141716 | CB1 antagonist