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Flupirtine maleate

D 9998 - Katadolon

CAS 75507-68-5

 C15H17FN4O2.C4H4O4 

MW 420.40  Purity: 99 %

Ordering Information:

Cat. No. Axon 1437 

Qty1: 10 mg / €65  $85

Qty2: 50 mg / €185  $241

Qty3: on request

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Biological Activity:   A centrally acting, nonopioid analgesic; flupirtine has a functional profile similar to NMDA-receptor antagonists, but devoid of the typical side effects of these drugs; flupirtine exerts potent cyto- and neuroprotective actions in different in vivo and in vitro models.   References: online 1, 2   MD Swedberg et al. Pharmacological mechanisms of action of flupirtine: a novel, centrally acting, nonopioid analgesic evaluated by its discriminative effects in the rat. J. Pharmacol. Exp. Ther. 1998, 246(3), 1067–74.   S Dhar et al. Flupirtine blocks apoptosis in batten patient lymphoblasts and in human postmitotic CLN3- and CLN2-deficient neurons. Ann. Neurol. 2002, 51 (4), 448–66.   G. Schuster et al. Flupirtine: A Review of Its Neuroprotective and Behavioral Properties. CNS Drug Reviews, 1998, 4(2), 149-164.     Chemical Name: N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl ]carbamic acid ethyl ester maleate

Flupirtine maleate | Analgesic | Axon Medchem | Axon 1437 | D 9998 - Katadolon

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Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.