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Ko143  -  Ko 143

CAS 461054-93-3

C26H36N3O5  MW 469.57

Purity: 99%

Ordering Information:

Cat. No. Axon 1409       Prime Source

Qty1: 2 mg / €85  $111

Qty2: 5 mg / €125  $163

Qty3: 25 mg / inquire

Qty4: on request

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Biological Activity:   Potent and selective inhibitor of breast cancer resistance protein (BCRP) multidrug transporter   References:   JD Allen et al. Potent and Specific Inhibition of the Breast Cancer Resistance Protein Multidrug Transporter in Vitro and in Mouse Intestine by a Novel Analogue of Fumitremorgin C.  Mol. Cancer Ther. 2002, 1, 417-425. [online]   A van Loevezijn et al. Inhibition of BCRP-mediated drug efflux by fumitremorgin-type indolyl diketopiperazines. Bioorg. Med. Chem. Lett. 2001, 11(1), 29-32. [abstract]     Chemical Name: 3-((3S,6S,12aS)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indol-3-yl)-propionic acid tert-butyl ester

Ko143 | BCRP inhibitor | Axon Medchem | Axon 1409 | Ko 143

Axon Ligands ^TM - Research chemicals for biological study. Some high-profile samples could be provided under terms of contract research synthesis.

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