NNC 756 - Odapipam | D1 antagonist | Axon Ligands | Axon Medchem

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NNC 756 - Odapipam

CAS 131796-63-9

C19H20ClINO2 MW 329.83

Purity: >99%, >99%ee

Ordering Information:

Cat. No. Axon 1405 Prime Source

Qty1: 5 mg / 135 $176

Qty1: 25 mg / 540 $702

Qty3: on request

Send enquiry to: order@axonmedchem.com

or by fax to: +31-50-3600390.

Biological Activity:

Very potent dopamine D1 antagonist.

References:

EB Nielsen, PH Andersen. Dopamine receptor occupancy in vivo: behavioral correlates using NNC-112, NNC-687 and NNC-756, new selective dopamine D1 receptor antagonists. Eur. J. Pharmacol. 1992, 219(1), 35-44; ibid 45-52.

A Abi-Dargham et al. PET studies of binding competition between endogenous dopamine and the D1 radiotracer [11C]NNC 756. Synapse. 1999, 32(2), 93-109. [online abstract]

Chemical Name: (S)-(+)-8-chloro-5-(2,3-dihydrobenzofuran-7-yl)-7-hydroxy-3-methyl-2,3,4,5- tetrahydro-1H-3-benzazepine

NNC 756 - Odapipam | D1 antagonist | Axon Medchem | Axon 1405 | NNC 0756 - NNC 01-0756